
BiOkuris Announces Positive Results from Pivotal IBS Study (Vitabiotic) Evaluating BK002
Read moreBiOkuris develops next generation medical nutrition products tailored to the unmet medical needs of patients with chronic intestinal diseases.
We believe that patients deserve specific, safe, effective, and science-driven treatments that reduce their daily burden and help them to restore balance.
Our solutions have been specifically designed to improve both the physiopathology and quality of life for the millions of patients living with chronic intestinal diseases.
Discover our innovative platformIBS is a public health problem that affects 10-20% of the population, predominantly affecting women in Europe and North America. With a peak level of frequency between the ages of 20 and 40, it causes young individuals to experience significantly disabling symptoms, resulting in a considerable reduction in their quality of life.
The physiopathology is complex and multifactorial, with existing treatments in Europe only providing a temporary relief of symptoms, without truly addressing the underlying causes. The margin of therapeutical gains when trialed together with placebos rarely exceeds 10%.
BiOkuris is committed to providing targeted, clinically-proven solutions for IBS patients, ensuring a complete and multifactorial effect on their physiopathology, thereby improving their quality of life.
40% of Crohn’s disease and ulcerative colitis patients with long-standing remission continue to experience IBS (Irritable Bowel Syndrome)-like symptoms.
Even during and after treatment involving biosimilars and a full control of inflammation, 40% of patients still suffer from abdominal pain, bloating, constipation, or diarrhea.
The etiology of IBS/IBS-like symptoms is multifactorial, combining hypersensitivity of the digestive tract, low-grade local inflammation, and changes in the intestinal flora with dysbiosis, increased intestinal permeability and bile acid malabsorption.
Existing and available drugs are only modestly effective, often developed to improve transit disorders and/or stool consistency via non-irritating laxatives for constipation, transit retarders for diarrhea, antispasmodics for bloating and anxiolytics.
Such ‘IBS-like symptoms’ in IBD patients need to be both comprehensively and specifically targeted to fully satisfy patients’ expectations and radically improve their quality of life.
Candida albicans is a type of yeast that can colonize any segment of the digestive tract or vagina. Its deleterious effects are well documented, ranging locally from potentially IBD-caused colitis to cutaneous-mucosal candidiasis, with vaginal candidiasis occurring in 75% of women at least once in their lives, and systemic infections that often occur in hospital, incurring significant medical and financial cost.
As the gut is the source of Candida albicans, targeting this commensal in the gut itself could reduce, even prevent, fungal infections in millions of people each year.
At BiOkuris, innovation begins with ScOpe™, our proprietary platform designed to create next-generation nutritional and medical solutions.
ScOpe™ reflects our core philosophy: leveraging ingredient synergies, scientific precision, and clinical efficacy to address complex health challenges.
Built on our two patented active ingredients – chitin-glucan and chitosan – both derived from nature, vegan, safe, and non-GMO, ScOpe™ enables the development of targeted formulations with proven benefits.
Backed by extensive in vitro, in vivo, and clinical studies, our platform has already demonstrated exceptional results, paving the way for innovative, science-driven solutions in gut health and beyond.
Biocopolymer of chitine betaglucan with prebiotic properties
Cationic biopolymer with antifungal and film forming capacities
We are opening a multitude of potential applications in various diseases in combination with other ingredients. This means that our ingredients hold the promise for innovative applications in treating diseases, from chronic conditions affecting the digestive system, such as IBS and IBD, to systemic issues like inflammation and immune system disorders.
The possibility of combining our ingredients with others opens up a new frontier in personalized medicine, where treatments can be tailored to the unique needs and conditions of individual patients.
Our company is located near Liege, in Belgium, and we benefit from the rich ecosystem of the “biotech-pharma valley” in Wallonia, allowing us to get access to the best resources to develop our projects. BiOkuris is part of the KitoZyme Group, who for the last 20 years has specialized in the design and manufacturing of biopolymers for Health & Nutrition, Agriculture and Personal Care.
BiOkuris stands at the forefront of gastrointestinal healthcare innovation.
Our nutritional solutions are designed to alleviate the symptoms and improve the lives of those affected by gastrointestinal conditions. Our focus lies in harnessing the power of natural biopolymers, chitin-glucan and chitosan, derived from Aspergillus niger, to create products with innovative synergies that offer real health benefits beyond traditional pharmaceuticals.
As a company, our work encompasses a comprehensive portfolio that extends from pre-clinical developments through to clinical studies, culminating in a commercial product that is establishing its presence in the market.
BiOkuris is led by a team combining expertise in Consumer Health, Pharmaceuticals, Biotechnology and Clinical Medicine.